Discover the benefits of Pantoprazole Sodium Sesquihydrate Tablet USP in managing acid-related disorders.
Key Features:
– Effective relief from heartburn
– Proven to reduce stomach acid
– Easy-to-take tablets for convenience
– Trusted USP formulation for quality assurance
Experience the power of Pantoprazole Sodium Sesquihydrate Tablet USP today!
Pantoprazole Sodium Sesquihydrate Tablet USP Monograph
The Pantoprazole Sodium Sesquihydrate Tablet USP is a prescription medication used for the treatment of certain conditions caused by excess stomach acid. It belongs to a class of drugs known as proton pump inhibitors, which work by reducing the amount of acid produced in the stomach.
This medication is commonly prescribed to treat conditions such as gastroesophageal reflux disease (GERD), ulcers, and Zollinger-Ellison syndrome. It helps relieve symptoms such as heartburn, acid indigestion, and stomach pain caused by excessive stomach acid.
The Pantoprazole Sodium Sesquihydrate Tablet USP comes in tablet form and is usually taken once daily before a meal. It is important to follow the dosage instructions provided by your healthcare provider to ensure the medication is effective.
| Brand Name | Pantoprazole Sodium Sesquihydrate Tablet USP |
|---|---|
| Generic Name | Pantoprazole |
| Drug Class | Proton Pump Inhibitor |
| Uses | Treatment of GERD, ulcers, and Zollinger-Ellison syndrome |
| Dosage Form | Tablet |
Overall, the Pantoprazole Sodium Sesquihydrate Tablet USP is a safe and effective medication for managing conditions related to excess stomach acid. It is important to consult with your healthcare provider before starting this medication to ensure it is appropriate for your individual needs.
Mechanism of Action
Pantoprazole sodium sesquihydrate tablet works by reducing the amount of acid produced in the stomach. It is a proton pump inhibitor that inhibits the enzyme H+/K+-ATPase in the gastric parietal cells, thereby reducing the production of gastric acid.
This inhibition of acid production helps in the treatment of conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and other acid-related disorders. By reducing the acidity in the stomach, pantoprazole sodium sesquihydrate tablet helps relieve symptoms such as heartburn, acid reflux, and difficulty swallowing.
It is important to follow the dosage and administration guidelines provided by your healthcare provider to ensure the optimal therapeutic effect of pantoprazole sodium sesquihydrate tablet. If you have any questions or concerns about the mechanism of action of this medication, consult with your healthcare provider for more information.
Mechanism of Action
The mechanism of action of Pantoprazole Sodium Sesquihydrate tablet involves the inhibition of the enzyme H+/K+ ATPase in the parietal cells of the stomach. This enzyme is responsible for the final step in the production of gastric acid in the stomach. By blocking this enzyme, Pantoprazole reduces the amount of acid produced, leading to a decrease in gastric acidity.
This mechanism of action allows Pantoprazole to be effective in the treatment of conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and other acid-related disorders. By lowering the acidity of the stomach, Pantoprazole helps to alleviate symptoms such as heartburn, acid reflux, and pain caused by excess stomach acid.
Indications and Usage
Pantoprazole Sodium Sesquihydrate Tablet USP is indicated for the short-term treatment of erosive esophagitis associated with gastroesophageal reflux disease (GERD).
It is also indicated for maintaining healing of erosive esophagitis and for long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison Syndrome.
Recommended Dosage
The recommended dosage of Pantoprazole Sodium Sesquihydrate Tablet USP for the treatment of erosive esophagitis is 40 mg once daily for up to 8 weeks.
For maintaining healing of erosive esophagitis, the recommended dosage is 40 mg once daily.
Dosage Adjustment in Renal Impairment
In patients with severe renal impairment, the recommended dosage of Pantoprazole Sodium Sesquihydrate Tablet USP is 20 mg once daily.
| Indication | Dosage |
|---|---|
| Erosive Esophagitis | 40 mg once daily for up to 8 weeks |
| Maintenance of Healing of Erosive Esophagitis | 40 mg once daily |
| Pathological Hypersecretory Conditions | Initial dose of 40 mg twice daily, then adjust according to response |
Dosage and Administration
Recommended Dosage:
The recommended dosage of Pantoprazole Sodium Sesquihydrate Tablet USP is 40 mg once daily for up to 8 weeks for the treatment of gastroesophageal reflux disease (GERD).
Administration:
Take Pantoprazole Sodium Sesquihydrate Tablet USP orally, with or without food, preferably before a meal. Swallow the tablet whole with a glass of water. Do not crush, break, or chew the tablet as it may affect the release of the drug.
Missed Dose:
If a dose is missed, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.
Storage:
Store Pantoprazole Sodium Sesquihydrate Tablet USP at room temperature away from moisture and heat. Keep out of reach of children.
Adverse Reactions
Common adverse reactions: The most common adverse reactions reported in patients taking Pantoprazole Sodium Sesquihydrate Tablet USP include headache, diarrhea, abdominal pain, nausea, and dizziness. These reactions are usually mild and transient.
Serious adverse reactions: Although rare, serious adverse reactions such as severe allergic reactions, Stevens-Johnson Syndrome, and toxic epidermal necrolysis have been reported with the use of Pantoprazole Sodium Sesquihydrate Tablet USP. Patients should seek medical attention immediately if they experience any severe adverse reactions.
Drug interactions: Pantoprazole Sodium Sesquihydrate Tablet USP may interact with certain medications, such as warfarin, atazanavir, and clopidogrel, leading to an increased risk of adverse reactions. Patients should inform their healthcare provider about all medications they are taking to avoid potential drug interactions.
Special populations: In special populations such as pediatric patients, elderly patients, and pregnant women, the risk of adverse reactions to Pantoprazole Sodium Sesquihydrate Tablet USP may be higher. Healthcare providers should monitor these populations closely for any signs of adverse reactions and adjust the dosage if necessary.
Overall, Pantoprazole Sodium Sesquihydrate Tablet USP is generally well-tolerated, but like any medication, it may cause adverse reactions in some patients. Patients should consult their healthcare provider if they experience any unexpected or severe adverse reactions while taking this medication.