Pantoprazole full prescribing information

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Discover everything you need to know about Pantoprazole with our comprehensive prescribing information.

Important: Please read this information carefully before using Pantoprazole.

Overview of Pantoprazole

Overview of Pantoprazole

Pantoprazole is a proton pump inhibitor (PPI) that is used to reduce the amount of acid produced in the stomach. It is commonly prescribed to treat conditions such as gastroesophageal reflux disease (GERD), ulcers, and Zollinger-Ellison syndrome.

Pantoprazole works by blocking the enzyme in the wall of the stomach that produces acid. This helps to relieve symptoms such as heartburn, regurgitation, and difficulty swallowing.

It is important to follow your healthcare provider’s instructions when taking Pantoprazole and to not exceed the recommended dosage. If you have any questions or concerns about this medication, be sure to talk to your doctor or pharmacist.

Uses and Indications

Pantoprazole is a proton pump inhibitor (PPI) indicated for the treatment of the following conditions:

Gastroesophageal Reflux Disease (GERD) Pantoprazole is used for the short-term treatment of GERD, including healing and symptom relief.
Erosive Esophagitis Pantoprazole is indicated for the healing of erosive esophagitis and maintenance of healing of erosive esophagitis.
Helicobacter Pylori Eradication Pantoprazole is used in combination with antibiotics for the eradication of Helicobacter pylori in patients with peptic ulcer disease.
Zollinger-Ellison Syndrome Pantoprazole is indicated for the long-term treatment of pathological hypersecretory conditions, such as Zollinger-Ellison Syndrome.
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Dosage and Administration

Dosage: The recommended dose of Pantoprazole is 40 mg once daily for up to 8 weeks for the healing and symptom relief of erosive esophagitis. For the maintenance of healing, the recommended dose is 40 mg once daily.

Administration: Pantoprazole should be taken at least 30 minutes before a meal. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose.

It is important to follow the prescribed dosage and administration instructions provided by your healthcare provider to ensure the best possible treatment outcomes.

Dosage and Administration

It is essential to follow the prescribed dosage and administration instructions for Pantoprazole to ensure its effectiveness and safety.


The typical dosage for Pantoprazole is 40 mg once daily for the treatment of conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. The dosage may vary based on the specific condition being treated and the individual’s response to the medication.


Pantoprazole tablets should be taken by mouth with or without food, as directed by your healthcare provider. It is essential to swallow the tablets whole and not crush, chew, or split them. If you have difficulty swallowing the tablets, consult your healthcare provider for alternative administration methods.

If you miss a dose of Pantoprazole, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double dose to make up for a missed dose.

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It is important to complete the full course of treatment with Pantoprazole as prescribed by your healthcare provider, even if you start to feel better before the treatment is completed.

Consult your healthcare provider if you have any questions or concerns about the dosage or administration of Pantoprazole.

Adverse Reactions

Adverse Reactions

Pantoprazole may cause some adverse reactions in some individuals. The most common side effects include headache, diarrhea, abdominal pain, and nausea. In some cases, more serious reactions such as allergic reactions or severe skin rashes may occur. It is important to contact your healthcare provider if you experience any unusual symptoms while taking Pantoprazole.

Drug Interactions

Pantoprazole may interact with other medications, causing potential side effects or diminishing the effectiveness of the treatment. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Pantoprazole.

Interactions with Medications:

Some medications that may interact with Pantoprazole include:

Medication Potential Interaction
Clopidogrel Pantoprazole can reduce the effectiveness of clopidogrel, increasing the risk of cardiovascular events.
Warfarin Pantoprazole may enhance the anticoagulant effect of warfarin, leading to an increased risk of bleeding.

Interactions with Food and Drinks:

Pantoprazole may interact with certain foods and drinks, such as grapefruit juice, which can affect the absorption of Pantoprazole into the bloodstream. It is advisable to avoid consuming grapefruit juice while taking Pantoprazole.

It is essential to consult your healthcare provider or pharmacist for a comprehensive list of potential interactions and take necessary precautions to avoid any adverse effects.

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Additional Information

Storage: Store pantoprazole at room temperature away from moisture and heat.

Pregnancy: It is not known whether pantoprazole can harm an unborn baby. Consult your healthcare provider if you are pregnant or planning to become pregnant.

Breastfeeding: Pantoprazole may pass into breast milk and could harm a nursing baby. Consult your healthcare provider before breastfeeding while using pantoprazole.